multiple myeloma

Symptoms Multiple Myeloma

Multiple Myeloma (MM) is a malignant plasma cell disease occurs in cells B lymphocytes in early stage of Multiple Myeloma, does not seem the obvious symptoms in patients, have to wait until a couple of years or even ten years more to develop into disease myeloma.


Symptoms – symptoms of Multiple Myeloma

　　(1) bone Pain: the main symptoms of myeloma, in 60% of cases the disease is generally starts from the lower part of the spine then up to the ribs of the chest. Firstly patients will experience intermittent pain which then gradually become persistent pain, the pain will be felt along with increasing activity.

(2) the presence of a lump on the bone: the vast majority occur in flat bones, especially in the sternum, ribs, skull, collarbone, lower jaw, etc. The presence of swelling of the bone occurs, when it touched feels when pressed hard and feels elastic or voiced, and the illness as because of the depressed. Tissue tumors often seen attacking the surrounding soft tissues, in half of the patients seen occurrence of changes on the breastbone (sternum), ribs, jaw bones in joints.

(3) Infection: an increase in myeloma patients on infection in the lungs, the urinary tract, skin, and sinuses. On the way the disease of patients with end-stage or in the process of chemotherapy often experience a relapsing infections are difficult to be controlled by drugs and is often the main cause of death.

(4) the weakening of body condition and Anemia (cachexia): due to the destruction of bone marrow hematopoietic system in the then nearly all anemic patients with different levels of severity and are also accompanied by the weakening of body condition, bleeding occurs due to thrombocytopenia, damage to blood vessels and koagulopati (blood freezing). Visible presence of hematoma and mucosal bleeding blue as the main symptoms of the final stage, in the presence of bleeding on the brain.

(5) Impaired Renal function: it often happens in the early onset of diseases, 20% of the patients experienced renal failure and uremia as a common cause of death in this disease.

(6) an abnormality imunoglobulin: an increasing number of monoclonal imunoglobulin cause increased blood viscosity, especially causing the blood flow slows and ganguan blood circulation, also known as hiperviskositas syndrome, blood visible presence bleeding capillaries, limb numbness, and brain dysfunction.

(7) the nervous system: the network of nerve tumor pathologic fractures and torakolumbar that suppress the spinal cord, it may cause symptoms such as paraplegia (paralysis on both limbs), difficult urination, neuralgia (pain nerve), numbness in the limbs and the presence of disorders of the body's movement system.

(8) Other symptoms: high levels of calcium, swelling of the liver and spleen (hepatosplenomegali), amyloidosis, and a small number of patients with cryoglobulinemia secondary Raynaud phenomenon is the existence of a look.

Modern Cancer Hospital of Guangzhou remind: If the symptoms arise as mentioned above, it can be a symptom of illness suspected multiple myeloma, then should immediately go to hospital for checks and treatment.